Bacteria to treat type 2 diabetes ?

Patrice Cani Published in the journal : May 2017 Category : Congrès UCL de Médecine Générale

Summary :

Obesity and Type 2 diabetes are both associated with low-grade inflammation. Among the possible pathomechanisms, their link to intestinal bacteria is becoming increasingly convincing. Evidence suggests that gut microbiota plays a key role in triggering inflammation and insulin resistance through various mechanisms, such as the translocation of bacteria or bacterial components that induces metabolic endotoxemia. Certain intestinal bacteria may also be either deleterious or beneficial to glucose homeostasis. Among these, the specific role of Akkermansia muciniphila is currently being investigated.

Key Words

Obesity, diabetes, gut microbiota, Akkermansia muciniphila, inflammation