In a world that is undergoing profound and accelerated mutations, medical schools are increasingly challenged and they must adapt and innovate in order to meet their societal requirements. During the last century, the concept of social accountability has gained momentum, thereby reflecting the need to render everyone aware of their interdependence with the whole society. Medical schools are getting organized to progressively implement this accountability, and its principles and projects, as well. In addition, this paper illustrates the commitment of the medical school of Université catholique de Louvain to become a socially-accountable institution.