Optimizing antihyperglycemic therapy in elderly people living with type 2 diabetes: challenges of overtreatment and deprescription

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Antoine Christiaens Published in the journal : March 2025 Category : 19e Congrès UCLouvain d’Endocrino-Diabétologie

Summary :

Type 2 diabetes treatment in older adults presents a clinical challenge due to a benefit-risk balance that is increasingly compromised by ageing and comorbidities. This review explores the concepts of overtreatment and deprescribing of glucose-lowering treatments, which are essential for optimizing the management of this heterogeneous population. Beyond highlighting their relevance, it underlines current knowledge gaps and the need for further research to develop a more individualized, effective, and safe therapeutic approach for older adults living with type 2 diabetes. 

Keywords

Type 2 diabetes, elderly people, personalization, overtreatment, deprescription