Guselkumab, an effective interleukin-23 inhibitor in the treatment of psoriasis

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Caroline Colmant, Pierre-Dominique Ghislain (1) Published in the journal : September 2018 Category : Actualité thérapeutique

Summary :

Guselkumab is a selective interleukin-23 inhibitor that has been marketed and reimbursed since a few months in Belgium. We conducted a literature review in order to assess the efficacy and safety of guselkumab.

What is already known about the topic?

Guselkumab is a selective interleukin (IL)-23 inhibitor that has been marketed and reimbursed since a few months in Belgium. IL-23 plays a role in the Th17 pathway, which is of key importance in the pathophysiology of psoriasis.

What does this article bring up for us?

This article offers a literature review on the efficacy and safety of guselkumab.

Keywords

Guselkumab, interleukin 23, psoriasis, biotherapy