Osteomyelitis is an infection that affects the bone tissue via hematogenous dissemination, direct post-traumatic or post-surgical inoculation, or a contiguous local infection, such as cellulitis or sinusitis. It is preferentially localized in the metaphyseal region of long bones. Short bones are more rarely affected. Sternal involvement is observed in about 1% of all pediatric osteomyelitis cases. Initial symptoms are often nonspecific, thus resulting in delayed diagnosis. Once the infection is established, symptoms of local inflammation appear. The treatment consists of a targeted antibiotic therapy depending on the child’s age and germs responsible for the infection.

A 53-year-old patient attended the emergency department, on two occasions, because of angina symptoms following the administration of 5-fluorouracil. This treatment was employed in a preoperative neoadjuvant approach in the setting of a recent diagnosis of colorectal cancer (T3N1M0).

Overall, 5-fluorouracil can be associated with cardiac toxicity that manifests itself as pectoral angina, infrequently resulting in irreversible, potentially lethal, cardiac pathologies. While multiple risk factors and action mechanisms have been proposed in the literature, they are still largely unknown among practitioners.

Brain cysticercosis, or neuro-cysticercosis, is an infection involving the central nervous system caused by larvae of a flat worm called Taenia solium. This infection may give rise to numerous different medical presentations, complicating its diagnosis.

The interest of this clinical case assessment describe in this article lies in the rarity of its diagnosis, its non-specific infectious manifestation, as well as the fact that the patient had not recently travelled to a cysticercosis-endemic area.

The adult-onset Still’s disease is a rare cause of fever of unknown origin. The clinical presentation and biological signs are rather polymorphous and non-specific. We herein emphasize the usefulness of measuring serum ferritin and glycosylated ferritin (GF) levels. The diagnosis of adult-onset Still’s disease is based on the Yamaguchi criteria, with three major criteria (high fever for more than 1 week, neutrophilic leucocytosis, and diffuse arthralgia) and three minor criteria (liver enzyme elevation of neither toxic nor drug-related origin, lymphadenopathy identified on PET imaging, and negativity of rheumatoid factors and antinuclear antibodies) to be present. The disease’s pathophysiology is still uncertain, and treatment essentially relies on systemic glucocorticoids. In this paper, we have discussed the usefulness of biotherapies, comprising primarily the monoclonal antibodies directed against the IL-6 receptor.