The systematic use of opioids has made us lose sight of their significant adverse effects, including respiratory distress, hyperalgesia, as well as postoperative nausea and vomiting. Sub-Saharan African countries are currently facing the issue of post-interventional surveillance, with post-operative respiratory problems being rather common. Similarly, these countries experience difficulties in managing pain, nausea, and vomiting. At times, opioid ruptures may occur, which may lead to postponing surgical procedures, in a context where access to surgery is already a obstacle. The opioid-free anesthesia could be an interesting alternative for these countries, especially when using accessible drugs with simple protocols. Therefore, anesthesiologists from these countries should focus their interest on such anesthesia techniques, in the aim to better define their place in their daily practice and share their potential benefits in a limited-resource setting.

Dual antiplatelet therapy consisting of aspirin in combination with clopidogrel, ticagrelor, or prasugrel is considered the standard of care for preventing stent thrombosis following percutaneous coronary angioplasty. However, adverse cardiovascular events may still occur despite such biotherapy. This can be explained by resistance to antiplatelet agents, with clopidogrel resistance the most widely studied so far. Some cases of resistance to other antiplatelet agents like prasugrel and ticagrelor have recently been reported. While laboratory tests have been developed to assess the degree of platelet inhibition under treatment, their clinical usefulness remains controversial. We herein report the case of a patient with a resistance to different antiplatelet agents.

Given that European and national legislation in the field of disability is particularly broad and complex, it is often misunderstood not only by persons with disabilities and their families but also by the general public, schools, public authorities, and politicians, in addition to public and private sector employers.

Moreover, persons with disabilities tend to face great difficulties in enforcing their rights. Inclusion starts with knowledge and respect of their most fundamental rights. This is the reason that has motivated the creation of DHEI, which is a new non-profit organization (NPO) that acts in the disability and inclusion field. As a legal support structure in the field of disability, this NPO seeks to make people with disabilities, their families, and healthcare professionals aware of the existing rights via two main axes: training courses in disability law and frontline legal assistance without cost for people with disabilities and their families. By combining both the human and technical aspects of the law, the DHEI actively works in collaboration with various network partners that share extensive expertise in the field of disability.